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Mitotane

[Chemical Name]:

1,1-Dichloro-2,2-bis(2,4'-dichlorophenyl)ethane; 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane

[Depression]:

A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

[Structure]:

[Formula]:C14H10Cl4

[Molecular Weight]:320.045

[CAS RN]:53-19-0

[Specification]:USP27/USP28

Appearance

White or off white

Identification

A

IR chromatograph conforms to characteristic peak of RS

B

UV chromatograph conforms to characteristic peak of RS

Melting range°C

75~81°C

Loss on drying

0.5%max

Residue on ignition

0.5%max

Organic volatile impurities

Meets the requirements

Assay (calculated on dried basis C14H10Cl4)

97.0~103.0%


 

 
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